概述

  • 产品名称人FGD1肽

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列C-TAEPPESPQTRDKT
    • 氨基酸948 to 961

技术指标

Our Abpromise guarantee covers the use of ab45555 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

常规信息

  • 别名
    • AAS
    • Faciogenital dysplasia 1 protein
    • FGD1
    • FGD1_HUMAN
    • FGDY
    • FYVE RhoGEF and PH domain containing protein 1
    • FYVE, RhoGEF and PH domain-containing protein 1
    • Rho/Rac GEF
    • Rho/Rac guanine nucleotide exchange factor FGD1
    • ZFYVE3
    • Zinc finger FYVE domain containing protein 3
    • Zinc finger FYVE domain-containing protein 3
    see all
  • 功能Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape.
  • 组织特异性Expressed in fetal heart, brain, lung, kidney and placenta. Less expressed in liver; adult heart, brain, lung, pancreas and skeletal muscle.
  • 疾病相关Aarskog-Scott syndrome
    Defects in FGD1 are found in a patient with non-syndromal X-linked mental retardation.
  • 序列相似性Contains 1 DH (DBL-homology) domain.
    Contains 1 FYVE-type zinc finger.
    Contains 2 PH domains.
  • 结构域The DH domain is involved in interaction with CCPG1.
  • 细胞定位Cytoplasm. Cell projection, lamellipodium. Cell projection, ruffle. Cytoplasm, cytoskeleton. Associated with membrane ruffles and lamellipodia.
  • Information by UniProt

Human FGD1 peptide (ab45555)参考文献

ab45555 has not yet been referenced specifically in any publications.

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