概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列C-PKEPSSYDFVYHYG
    • 氨基酸707 to 720

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技术指标

Our Abpromise guarantee covers the use of ab22879 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-ELMO2 antibody (ab2240)

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • CED 12
    • Ced 12 homolog 2
    • CED 12 homolog A
    • CED 12A
    • CED-12
    • ced-12 homolog 2
    • CED12
    • CED12 homolog A
    • CED12, C. elegans, homolog of, 2
    • CED12A
    • ELMO 2
    • ELMO-2
    • ELMO2
    • ELMO2_HUMAN
    • Engulfment and cell motility 2
    • Engulfment and cell motility 2 (ced 12 homolog, C. elegans)
    • Engulfment and cell motility gene 2
    • Engulfment and cell motility protein 2
    • FLJ11656
    • hCED 12A
    • hCED-12A
    • hCED12A
    • KIAA1834
    • OTTHUMP00000031762
    • PH domain protein CED12A
    • Protein ced 12 homolog A
    • Protein ced-12 homolog A
    see all
  • 功能Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
  • 组织特异性Widely expressed, with a higher expression in skeletal muscle, kidney and placenta.
  • 序列相似性Contains 1 ELMO domain.
    Contains 1 PH domain.
  • 细胞定位Cytoplasm. Cytoplasm > cytosol. Membrane.
  • Information by UniProt

Human ELMO2 peptide (ab22879)参考文献

ab22879 has not yet been referenced specifically in any publications.

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