概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列PKEPSNYDFVYDCN
    • 氨基酸714 to 727

相关产品

技术指标

Our Abpromise guarantee covers the use of ab22878 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-ELMO1 antibody (ab2239)

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • CED 12
    • Ced 12 homolog
    • Ced 12 homolog 1
    • CED-12
    • CED12
    • Ced12 homolog
    • Ced12 homolog 1
    • ELMO 1
    • ELMO-1
    • Elmo1
    • ELMO1_HUMAN
    • Engulfment and cell motility 1
    • Engulfment and cell motility protein 1
    • KIAA0281
    • MGC126406
    • Protein ced-12 homolog
    see all
  • 功能Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
  • 组织特异性Widely expressed, with a higher expression in the spleen and placenta.
  • 序列相似性Contains 1 ELMO domain.
    Contains 1 PH domain.
  • 翻译后修饰Phosphorylated by HCK.
  • 细胞定位Cytoplasm. Cell membrane. Translocation to plasma membrane seems to be mediated by DOCK1 and CRK.
  • Information by UniProt

Human ELMO1 peptide (ab22878)参考文献

ab22878 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab22878.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"