概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列C-DNEDSDTKKSYVN
    • 氨基酸493 to 505

技术指标

Our Abpromise guarantee covers the use of ab48052 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

常规信息

  • 别名
    • EAA3_HUMAN
    • EAAC 1
    • EAAC1
    • EAAT 3
    • Excitatory amino acid carrier 1
    • Excitatory amino acid carrier1
    • Excitatory amino acid transporter 3
    • Excitatory amino acid transporter3
    • Excitatory amino-acid carrier 1
    • GLUTAMATE TRANSPORTER, HIGH-AFFINITY
    • MEAAC 1
    • MEAAC1
    • Neuronal and epithelial glutamate transporter
    • REAAC 1
    • REAAC1
    • Slc1 a1
    • Slc1a 1
    • SLC1A1
    • Sodium dependent glutamate/aspartate transporter 3
    • Sodium-dependent glutamate/aspartate transporter 3
    • Solute carrier family 1 (neuronal / epithelial high affinity glutamate transporter, system Xag), member 1
    • SOLUTE CARRIER FAMILY 1 (NEURONAL/EPITHELIAL HIGH AFFINITY GLUTAMATE TRANSPORTER), MEMBER 1
    • Solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
    • Solute carrier family 1 member 1
    • Solute carrier family 1, member 1
    see all
  • 功能Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. Negatively regulated by ARL6IP5.
  • 组织特异性Expressed in all tissues tested including liver, muscle, testis, ovary, retinoblastoma cell line, neurons and brain (in which there was dense expression in substantia nigra, red nucleus, hippocampus and in cerebral cortical layers).
  • 序列相似性Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A1 subfamily.
  • 翻译后修饰Glycosylated.
  • 细胞定位Membrane.
  • Information by UniProt

Human EAAT3 peptide (ab48052)参考文献

ab48052 has not yet been referenced specifically in any publications.

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