概述

描述

  • 性质
    Synthetic
  • 氨基酸序列
    • 种属
      Human
    • 序列
      C-DNEDSDTKKSYVN
    • 氨基酸
      493 to 505

技术指标

Our Abpromise guarantee covers the use of ab48052 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

常规信息

  • 别名
    • EAA3_HUMAN
    • EAAC 1
    • EAAC1
    • EAAT 3
    • Excitatory amino acid carrier 1
    • Excitatory amino acid carrier1
    • Excitatory amino acid transporter 3
    • Excitatory amino acid transporter3
    • Excitatory amino-acid carrier 1
    • GLUTAMATE TRANSPORTER, HIGH-AFFINITY
    • MEAAC 1
    • MEAAC1
    • Neuronal and epithelial glutamate transporter
    • REAAC 1
    • REAAC1
    • Slc1 a1
    • Slc1a 1
    • SLC1A1
    • Sodium dependent glutamate/aspartate transporter 3
    • Sodium-dependent glutamate/aspartate transporter 3
    • Solute carrier family 1 (neuronal / epithelial high affinity glutamate transporter, system Xag), member 1
    • SOLUTE CARRIER FAMILY 1 (NEURONAL/EPITHELIAL HIGH AFFINITY GLUTAMATE TRANSPORTER), MEMBER 1
    • Solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
    • Solute carrier family 1 member 1
    • Solute carrier family 1, member 1
    see all
  • 功能
    Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. Negatively regulated by ARL6IP5.
  • 组织特异性
    Expressed in all tissues tested including liver, muscle, testis, ovary, retinoblastoma cell line, neurons and brain (in which there was dense expression in substantia nigra, red nucleus, hippocampus and in cerebral cortical layers).
  • 序列相似性
    Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A1 subfamily.
  • 翻译后修饰
    Glycosylated.
  • 细胞定位
    Membrane.
  • Information by UniProt

文献

ab48052 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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