概述

  • 产品名称人DLL3肽

描述

  • 性质Synthetic

相关产品

技术指标

Our Abpromise guarantee covers the use of ab88189 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-DLL3 antibody (ab63707)

  • 纯度70 - 90% by HPLC.

  • 形式Liquid
  • 补充说明

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

常规信息

  • 别名
    • Delta Drosophila like 3
    • Delta like 3 Drosophila
    • Delta like 3 homolog Drosophila
    • Delta like 3 protein
    • Delta like protein 3 precursor
    • Delta-like protein 3
    • Delta3
    • Dll3
    • DLL3_HUMAN
    • Drosophila Delta homolog 3
    • SCDO1
    • SCOD1
    • Spondylocostal dysostosis autosomal recessive
    see all
  • 功能Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm.
  • 疾病相关Spondylocostal dysostosis 1
  • 序列相似性Contains 1 DSL domain.
    Contains 6 EGF-like domains.
  • 结构域The DSL domain is required for binding to the Notch receptor.
  • 翻译后修饰Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation.
  • 细胞定位Membrane.
  • Information by UniProt

Human DLL3 peptide (ab88189)参考文献

ab88189 has not yet been referenced specifically in any publications.

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