概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列C-QVLTKNKDNHN
    • 氨基酸571 to 581

相关产品

技术指标

Our Abpromise guarantee covers the use of ab48045 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-Dcp1a antibody (ab47998)

  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

  • 复溶Please reconstitute this product in 100ul sterile water.

常规信息

  • 别名
    • DCP1 decapping enzyme homolog A
    • Dcp1a
    • DCP1A_HUMAN
    • Decapping enzyme hDcp1a
    • Decapping mRNA 1A
    • HSA275986
    • mRNA decapping enzyme 1A
    • mRNA-decapping enzyme 1A
    • Nbla00360
    • Putative protein product of Nbla00360
    • Smad4 interacting transcriptional co activator
    • Smad4-interacting transcriptional co-activator
    • Smad4-interacting transcriptional co-activator
    • SMAD4IP1
    • SMIF
    • Transcription factor SMIF
    see all
  • 功能Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1.
  • 组织特异性Detected in heart, brain, placenta, lung, skeletal muscle, liver, kidney and pancreas.
  • 序列相似性Belongs to the DCP1 family.
  • 细胞定位Cytoplasm > P-body. Nucleus. Co-localizes with NANOS3 in the processing bodies (By similarity). Predominantly cytoplasmic, in processing bodies (PB). Nuclear, after TGFB1 treatment. Translocation to the nucleus depends on interaction with SMAD4.
  • Information by UniProt

Human Dcp1a peptide (ab48045)参考文献

ab48045 has not yet been referenced specifically in any publications.

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