概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列HQQDKAQKQEDKH

技术指标

Our Abpromise guarantee covers the use of ab45481 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

常规信息

  • 别名
    • CAP GLY domain containing linker protein 2
    • CAP-Gly domain-containing linker protein 2
    • CLIP
    • CLIP 115
    • CLIP-115
    • Clip2
    • CLIP2_HUMAN
    • cytoplasmic linker 2
    • Cytoplasmic linker protein 115
    • Cytoplasmic linker protein 2
    • KIAA0291
    • MGC11333
    • restin
    • Similar to RESTIN (CYTOPLASMIC LINKER PROTEIN 170 ALPHA 2)
    • WBSCR3
    • WBSCR4
    • Williams Beuren syndrome chromosome region 3
    • Williams Beuren syndrome chromosome region 4
    • Williams-Beuren syndrome chromosomal region 3 protein
    • Williams-Beuren syndrome chromosomal region 4 protein
    • WSCR3
    • WSCR4
    see all
  • 功能Seems to link microtubules to dendritic lamellar body (DLB), a membranous organelle predominantly present in bulbous dendritic appendages of neurons linked by dendrodendritic gap junctions. May operates in the control of brain-specific organelle translocations.
  • 疾病相关Note=CLIP2 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of CLIP2 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.
  • 序列相似性Contains 2 CAP-Gly domains.
  • 细胞定位Cytoplasm. Cytoplasm > cytoskeleton. Associated with the cytoskeleton.
  • Information by UniProt

Human CYLN2 peptide (ab45481)参考文献

ab45481 has not yet been referenced specifically in any publications.

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