- 氨基酸438 to 450
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-CSK antibody (ab744)
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- C SRC
- C SRC kinase
- C src Tyrosine Kinase
- 功���Specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site. Can also act on the LYN and FYN kinases.
- 组织特异性Expressed in lung and macrophages.
- 序列相似性Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.
Contains 1 protein kinase domain.
Contains 1 SH2 domain.
Contains 1 SH3 domain.
- 翻译后修饰Autophosphorylation of Tyr-304 occurs only at abnormally high CSK concentrations in vitro.
- 细胞定位Cytoplasm. Cell membrane. Mainly cytoplasmic, also present in lipid rafts.
Information by UniProt
Human CSK peptide (ab19039)参考文献
has not yet been referenced specifically in any publications.
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