概述

描述

  • 性质Synthetic

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技术指标

Our Abpromise guarantee covers the use of ab99478 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 纯度70 - 90% by HPLC.

  • 形式Liquid
  • 补充说明

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

常规信息

  • 别名
    • Collapsin response mediator protein
    • Collapsin response mediator protein 2
    • Collapsin response mediator protein hCRMP 2
    • CRAM
    • CRMP 2
    • CRMP-2
    • CRMP2
    • DHPRP 2
    • DHPRP2
    • Dihydropyrimidinase 2
    • Dihydropyrimidinase like 2
    • Dihydropyrimidinase like 2 long form
    • Dihydropyrimidinase related protein 2
    • Dihydropyrimidinase-related protein 2
    • DPYL 2
    • DPYL2
    • DPYL2_HUMAN
    • DPYSL 2
    • Dpysl2
    • DRP-2
    • DRP2
    • Musunc 33
    • Musunc33
    • N2A3
    • TOAD 64
    • TOAD64
    • ULIP 2 protein
    • ULIP-2
    • Ulip2
    • Unc-33-like phosphoprotein 2
    see all
  • 功能Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
  • 组织特异性Ubiquitous.
  • 序列相似性Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
  • 翻译后修饰3F4, a monoclonal antibody which strongly stains neurofibrillary tangles in Alzheimer disease brains, specifically labels DPYSL2 when phosphorylated on Ser-518, Ser-522 and Thr-509.
  • 细胞定位Cytoplasm.
  • Information by UniProt

Human CRMP2 peptide (ab99478)参考文献

ab99478 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"