概述

  • 产品名称人CCKAR肽

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列RFLLPPNDVMQQSWH
    • 氨基酸197 to 210

相关产品

技术指标

Our Abpromise guarantee covers the use of ab42262 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-CCKAR antibody (ab14441)

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 0.1% Acetic acid

常规信息

  • 别名
    • CCK A
    • CCK A receptor
    • CCK AR
    • CCK-A receptor
    • CCK1 R
    • CCK1-R
    • CCK1R
    • CCKA
    • CCKA receptor
    • CCKR Type A
    • CCKRA
    • Cholecystokinin 1 receptor
    • Cholecystokinin A receptor
    • Cholecystokinin receptor type A
    • Cholecystokinin type A receptor
    see all
  • 相关性The cholecystokinin (CCK) family of peptide hormones have been implicated in numerous important physiologic events. These appear to be mediated through 2 general classes of receptors, A (CCKAR)and B (CCKBR), based on their binding affinities for CCK/gastrin family peptides. Through binding to class A receptors, CCK is a major physiologic mediator of gallbladder contraction and pancreatic enzyme secretion. It appears to play a role in slowing gastric emptying, relaxation of the sphincter of Oddi, and potentiation of insulin secretion. Further, it has been implicated as a mediator of pancreatic growth and tumorigenesis. Class A receptors have also been described in the anterior pituitary, myenteric plexus, and regions of the central nervous system, where they have been implicated in the pathogenesis of feeding disorders, Parkinson disease, schizophrenia, and drug addiction.
  • 细胞定位Integral membrane protein

Human CCKAR peptide (ab42262)参考文献

ab42262 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"