概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列C-HGQFVSEKRVEQW
    • 氨基酸265 to 277

相关产品

技术指标

Our Abpromise guarantee covers the use of ab22991 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-CBR1 antibody (ab4148)

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • 15 hydroxyprostaglandin dehydrogenase [NADP+]
    • 15-hydroxyprostaglandin dehydrogenase [NADP+]
    • Carbonyl reductase [NADPH] 1
    • Carbonyl Reductase 1
    • CBR 1
    • CBR1
    • CBR1_HUMAN
    • CRN
    • NADPH dependent carbonyl reductase 1
    • NADPH-dependent carbonyl reductase 1
    • Prostaglandin 9 ketoreductase
    • Prostaglandin 9-ketoreductase
    • Prostaglandin E(2) 9 reductase
    • Prostaglandin-E(2) 9-reductase
    • SDR21C1
    see all
  • 功能NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.
  • 序列相似性Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  • 细胞定位Cytoplasm.
  • Information by UniProt

Human CBR1 peptide (ab22991)参考文献

ab22991 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"