概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列MPRVVPDQRSKFENEEFFRK
    • 氨基酸1 to 20

相关产品

技术指标

Our Abpromise guarantee covers the use of ab41799 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Neutralising

    Blocking - Blocking peptide for Anti-CBFb antibody (ab33516)

  • 形式Liquid
  • 补充说明Purity of this peptide: >70%
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

常规信息

  • 别名
    • CBF b
    • CBF beta
    • CBF-beta
    • CBFB
    • CBFbeta
    • Core binding factor beta subunit
    • core binding factor subunit beta
    • Core-binding factor subunit beta
    • PEA 2
    • PEA2
    • PEA2 beta
    • PEA2-beta
    • PEA2beta
    • PEBB_HUMAN
    • PEBP 2B
    • PEBP2 beta
    • PEBP2-beta
    • PEBP2B
    • PEBP2beta
    • Polyomavirus enhancer binding protein 2 beta subunit
    • Polyomavirus enhancer-binding protein 2 beta subunit
    • SL3 3 enhancer factor 1 beta subunit
    • SL3 3 enhancer factor 1 subunit beta
    • SL3-3 enhancer factor 1 subunit beta
    • SL3/AKV core binding factor beta subunit
    • SL3/AKV core-binding factor beta subunit
    see all
  • 功能CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3 and GM-CSF promoters. CBFB enhances DNA binding by RUNX1.
  • 疾病相关Note=A chromosomal aberration involving CBFB is associated with acute myeloid leukemia of M4EO subtype. Pericentric inversion inv(16)(p13;q22). The inversion produces a fusion protein that consists of the 165 N-terminal residues of CBF-beta (PEPB2) with the tail region of MYH11.
  • 序列相似性Belongs to the CBF-beta family.
  • 细胞定位Nucleus.
  • Information by UniProt

Human CBFb peptide (ab41799)参考文献

ab41799 has not yet been referenced specifically in any publications.

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