概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human

技术指标

Our Abpromise guarantee covers the use of ab39725 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

常规信息

  • 别名
    • Apoptotic cysteine protease Mih1/TX
    • CASP-4
    • CASP4
    • CASP4_HUMAN
    • Caspase 4 apoptosis related cysteine peptidase
    • Caspase-4 subunit 2
    • Caspase4
    • ICE(rel)-II
    • ICE(rel)II
    • ICEREL II
    • ICH2
    • Mih1/TX
    • Protease ICH-2
    • Protease TX
    • TX
    see all
  • 功能Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves caspase-1.
  • 组织特异性Widely expressed, with highest levels in spleen and lung. Moderate expression in heart and liver, low expression in skeletal muscle, kidney and testis. Not found in the brain.
  • 序列相似性Belongs to the peptidase C14A family.
    Contains 1 CARD domain.
  • 翻译后修饰The two subunits are derived from the precursor sequence by an autocatalytic mechanism or by cleavage by Caspase-8.
  • Information by UniProt

Human Caspase 4 peptide (ab39725)参考文献

ab39725 has not yet been referenced specifically in any publications.

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