概述

描述

  • 性质
    Synthetic
  • 氨基酸序列
    • 种属
      Human
    • 序列
      DRENTTGSDNTDTEGS amino acids 521 to 536 of human CARD9 (1).
    • 氨基酸
      521 to 536

相关产品

技术指标

Our Abpromise guarantee covers the use of ab9650 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    PBS with 0.1% BSA 0.02% sodium azide pH7.2

常规信息

  • 别名
    • CANDF2
    • CARD9
    • CARD9_HUMAN
    • Caspase recruitment domain family member 9
    • Caspase recruitment domain-containing protein 9
    • hCARD9
    see all
  • 功能
    Activates NF-kappa-B via BCL10.
  • 组织特异性
    Highly expressed in spleen. Also detected in liver, placenta, lung, peripheral blood leukocytes and in brain.
  • 疾病相关
    Defects in CARD9 are the cause of familial candidiasis type 2 (CANDF2) [MIM:212050]. Chronic mucocutaneous candidiasis is characterized by impaired clearance of fungal infections and results in colonization and infections of the mucosa or skin, predominantly with Candida albicans. CANDF2 is an autosomal recessive chronic mucocutaneous candidiasis.
  • 序列相似性
    Contains 1 CARD domain.
  • 细胞定位
    Cytoplasm.
  • Information by UniProt

Human CARD9 peptide (ab9650)参考文献

ab9650 has not yet been referenced specifically in any publications.

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