概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human

相关产品

技术指标

Our Abpromise guarantee covers the use of ab39738 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    Blocking - Blocking peptide for Anti-CARD8 antibody (ab24186)

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

常规信息

  • 别名
    • Apoptotic protein NDPP 1
    • Apoptotic protein NDPP1
    • CARD 8
    • CARD inhibitor of NF kappa B activating ligand
    • CARD inhibitor of NF kappaB activating ligand
    • CARD inhibitor of NF kappaB activating ligands
    • CARD-inhibitor of NF-kappa-B-activating ligand
    • CARD8
    • CARD8_HUMAN
    • CARDINAL
    • Caspase recruitment domain containing protein 8
    • Caspase recruitment domain family member 8
    • Caspase recruitment domain protein 8
    • Caspase recruitment domain-containing protein 8
    • DACAR
    • Dakar
    • DKFZp779L0366
    • FLJ18119
    • FLJ18121
    • KIAA0955
    • MGC57162
    • NDPP
    • NDPP 1
    • NDPP1
    • TUCAN
    • Tumor up regulated CARD containing antagonist of CASP9
    • Tumor up regulated CARD containing antagonist of caspase 9
    • Tumor up-regulated CARD-containing antagonist of CASP9
    • tumor up-regulated CARD-containing antagonist of caspase nine
    • Tumor upregulated CARD containing antagonist of CASP9
    see all
  • 功能Inhibits NF-kappa-B activation. May participate in a regulatory mechanism that coordinates cellular responses controlled by NF-kappa-B transcription factor. May be a component of the inflammasome, a protein complex which also includes PYCARD, NALP2 and CASP1 and whose function would be the activation of proinflammatory caspases.
  • 组织特异性High expression in lung, ovary, testis and placenta. Lower expression in heart, kidney and liver. Also expressed in spleen, lymph node and bone marrow.
  • 序列相似性Contains 1 CARD domain.
  • 细胞定位Cytoplasm. Nucleus.
  • Information by UniProt

Human CARD8 peptide (ab39738)参考文献

ab39738 has not yet been referenced specifically in any publications.

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