概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ
    • 氨基酸57 to 87

相关产品

技术指标

Our Abpromise guarantee covers the use of ab93903 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-C Peptide antibody (ab14181)

  • 形式Lyophilised
  • 补充说明

    C Peptide is part of the molecule of Proinsulin, that consists of three parts: C Peptide and two long strands of amino acids (called the alpha and beta chains) that later become linked together to form the insulin molecule. From every molecule of proinsulin, one molecule of insulin plus one molecule of C Peptide are produced. C peptide is released into the blood stream in equal amounts to insulin. A test of C peptide levels will show how much insulin the body is making. Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.

    This peptide can be used with studies using ab14181.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

  • 复溶Resuspend in 0.1% acetic acid for required concentration

常规信息

  • 别名
    • IDDM 2
    • IDDM2
    • ILPR
    • ins
    • INS_HUMAN
    • Insulin A chain
    • IRDN
    • MODY10
    • Proinsulin
    see all
  • 功能Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
  • 疾病相关Defects in INS are the cause of familial hyperproinsulinemia (FHPRI) [MIM:176730].
    Defects in INS are a cause of diabetes mellitus insulin-dependent type 2 (IDDM2) [MIM:125852]. IDDM2 is a multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
    Defects in INS are a cause of diabetes mellitus permanent neonatal (PNDM) [MIM:606176]. PNDM is a rare form of diabetes distinct from childhood-onset autoimmune diabetes mellitus type 1. It is characterized by insulin-requiring hyperglycemia that is diagnosed within the first months of life. Permanent neonatal diabetes requires lifelong therapy.
    Defects in INS are a cause of maturity-onset diabetes of the young type 10 (MODY10) [MIM:613370]. MODY10 is a form of diabetes that is characterized by an autosomal dominant mode of inheritance, onset in childhood or early adulthood (usually before 25 years of age), a primary defect in insulin secretion and frequent insulin-independence at the beginning of the disease.
  • 序列相似性Belongs to the insulin family.
  • 细胞定位Secreted.
  • Information by UniProt

Human C Peptide peptide (ab93903)参考文献

ab93903 has not yet been referenced specifically in any publications.

Product Wall

I agree the antibodies should detect the proteins in serum; as this is not the case so I am happy to replace these products. Would you like try new vials of these antibodies or a different antibody against the same target?
My suggestion would be tr...

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Thank you very much for confirming details.
The protein ab93903 has not been tested in ELISA and in combination with ab8297, ab8298 and ab48303 so we unfortunately do not hold any ELISA data for this product. This product was in fact used as blocki...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"