概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • AccessionP16860
    • 种属Human
    • 序列SPKMVQGSGCFGRKMDRISSSSGLGCKVLRRH-OH
    • 分子量3 kDa including tags
    • 氨基酸103 to 134

技术指标

Our Abpromise guarantee covers the use of ab123777 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    HPLC

    SDS-PAGE

  • 纯度> 98 % SDS-PAGE.
    Purity is greater than 98% as determined by HPLC and SDS-PAGE.
  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -20ºC.

  • 复溶Centrifuge the vial prior to opening. Reconstitute in sterile H2O to a concentration = 100 µg/ml. This solution can then be diluted into other aqueous buffers. Reconstituted ab123777 should be stored at 4°C for 2-7 days and at -20°C for future use. For long term storage it is recommended to add a carrier protein (0.1 % HSA or BSA) and store as working aliquots at -20°C.

常规信息

  • 别名
    • BNP(1-28)
    • BNP(1-29)
    • BNP(1-30)
    • BNP(1-32)
    • BNP(2-31)
    • BNP(3-29)
    • BNP(3-30)
    • BNP(3-32)
    • BNP(4-27)
    • BNP(4-29)
    • BNP(4-30)
    • BNP(4-31)
    • BNP(4-32)
    • BNP(5-29)
    • BNP(5-31)
    • BNP(5-32)
    • Brain natriuretic peptide 32
    • Brain type natriuretic peptide
    • Gamma brain natriuretic peptide
    • Natriuretic peptide B
    • Natriuretic peptide precursor B
    • natriuretic peptide, brain type
    • Natriuretic peptides B
    • natriuretic protein
    • NPPB
    see all
  • 相关性Brain natriuretic peptide (BNP) circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. BNP is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. BNP belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C type natriuretic peptide (CNP) and urodilatin. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic peptides (eleven of the 17 amino acid residues are homologous in the ring of each of the natriuretic peptides). BNP is a 32 amino acid peptide with disulfide bond between the cysteine residues Cys10 and Cys26. In earlier studies it has been demonstrated that BNP concentration in blood increases with the severity of congestive heart failure. Quantitative measurement of BNP in blood provides an objective indicator of congestive heart failure severity.
  • 细胞定位Secreted

Human BNP peptide (ab123777)参考文献

ab123777 has not yet been referenced specifically in any publications.

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