概述

描述

  • 性质
    Synthetic
  • 氨基酸序列
    • 种属
      Human
    • 序列
      C-SSMTDTPGNPAAP
    • 氨基酸
      563 to 575

相关产品

技术指标

Our Abpromise guarantee covers the use of ab23111 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-Bag3 antibody (ab5898)

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • BAG 3
    • BAG family molecular chaperone regulator 3
    • BAG-3
    • Bag3
    • BAG3_HUMAN
    • Bcl 2 binding protein
    • Bcl-2-associated athanogene 3
    • Bcl-2-binding protein Bis
    • BCL2 associated athanogene 3
    • BCL2 binding athanogene 3
    • BIS
    • CAIR 1
    • Docking protein CAIR 1
    • Docking protein CAIR-1
    • MFM6
    see all
  • 功能
    Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Has anti-apoptotic activity.
  • 疾病相关
    Defects in BAG3 are the cause of myopathy myofibrillar BAG3-related (MFM-BAG3) [MIM:612954]. A neuromuscular disorder that results in early-onset, severe, progressive, diffuse muscle weakness associated with cardiomyopathy, severe respiratory insufficiency during adolescence, and a rigid spine in some patients. At ultrastructural level, muscle fibers display structural alterations consisting of replacement of the normal myofibrillar markings by small, dense granules, or larger hyaline masses, or amorphous material.
  • 序列相似性
    Contains 1 BAG domain.
    Contains 2 WW domains.
  • Information by UniProt

文献

ab23111 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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