概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列C-KYAPKAASAPTDL
    • 氨基酸222 to 234

技术指标

Our Abpromise guarantee covers the use of ab22811 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • Arginine rich mutated in early stage tumors
    • Arginine rich protein
    • Arginine-rich protein
    • ARMET
    • ARMET protein
    • ARP
    • Manf
    • MANF_HUMAN
    • Mesencephalic astrocyte derived neurotrophic factor
    • Mesencephalic astrocyte-derived neurotrophic factor
    • MGC142148
    • MGC142150
    • Protein ARMET
    see all
  • 功能Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
  • 序列相似性Belongs to the ARMET family.
  • 结构域The N-terminal region may be responsible for neurotrophic activity while the C-terminal region may play a role in the ER stress response.
  • 翻译后修饰May contain sialic acid residues.
  • 细胞定位Secreted.
  • Information by UniProt

Human ARMET peptide (ab22811)参考文献

ab22811 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"