概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列C-AFTADPLSLLRNV
    • 氨基酸1198 to 1210

相关产品

技术指标

Our Abpromise guarantee covers the use of ab23119 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-ARAP1 antibody (ab5912)

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • 2410002L19Rik
    • ANK repeat and PH domain-containing protein 1
    • ARAP 1
    • Arap1
    • ARAP1_HUMAN
    • Arf GAP Rho GAP ankyrin repeat and pleckstrin homology domains containing protein 1
    • Arf GAP Rho GAP ankyrin repeat and pleckstrin homology domain containing protein 1
    • Arf-GAP with Rho-GAP domain
    • CENT D2
    • Centaurin delta 2
    • Centaurin delta2
    • Centaurin-delta-2
    • CENTD 2
    • CENTD2
    • Cnt d2
    • Cnt-d2
    • Cntd2
    • KIAA0782
    • MGC176140
    • mKIAA0782
    see all
  • 功能Phosphatidylinositol-3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol-3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Has a preference for ARF1 and ARF5.
  • 组织特异性Detected in heart, skeletal muscle, spleen, kidney, liver, placenta, lung, peripheral blood leukocytes, adrenal gland, bone marrow, brain, lymph node, mammary gland, prostate, spinal cord, stomach, thyroid and trachea.
  • 序列相似性Contains 1 Arf-GAP domain.
    Contains 4 PH domains.
    Contains 1 Ras-associating domain.
    Contains 1 Rho-GAP domain.
    Contains 1 SAM (sterile alpha motif) domain.
  • 细胞定位Cytoplasm. Golgi apparatus > Golgi stack membrane. Cell membrane. Associated with Golgi stacks in resting cells. Throughout the cytoplasm and in surface protrusion in cells that are in the process of attaching to a surface and spreading.
  • Information by UniProt

Human ARAP1 peptide (ab23119)参考文献

ab23119 has not yet been referenced specifically in any publications.

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