概述

描述

  • 性质Synthetic

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技术指标

Our Abpromise guarantee covers the use of ab103557 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-Amylin antibody (ab77387)

  • 纯度70 - 90% by HPLC.

  • 形式Liquid
  • 补充说明

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

常规信息

  • 别名
    • Amylin
    • DAP
    • Diabetes associated peptide
    • Diabetes-associated peptide
    • IAP
    • IAPP
    • IAPP_HUMAN
    • Insulinoma amyloid peptide
    • Islet amyloid polypeptide
    • Islet amyloid polypeptide (diabetes associated peptide; amylin)
    see all
  • 功能Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
  • 序列相似性Belongs to the calcitonin family.
  • 结构域The mature protein is largely unstructured in the absence of a cognate ligand, and has a strong tendency to form fibrillar aggregates. Homodimerization may be the first step of amyloid formation.
  • 翻译后修饰Amyloid fibrils are degraded by IDE.
  • 细胞定位Secreted.
  • Information by UniProt

Human Amylin peptide (ab103557)参考文献

ab103557 has not yet been referenced specifically in any publications.

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