概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列C-DAGHPLYPFNDPY
    • 氨基酸312 to 324

相关产品

技术指标

Our Abpromise guarantee covers the use of ab23210 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-AKR1A1 antibody (ab11802)

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • AK1A1_HUMAN
    • Akr1a1
    • Alcohol dehydrogenase
    • Alcohol dehydrogenase [NADP+]
    • Aldehyde reductase
    • Aldo keto reductase family 1 member A1 (aldehyde reductase)
    • Aldo-keto reductase family 1 member A1
    • ALDR1
    • ALR
    • ARM
    • DD3
    • MGC12529
    • MGC1380
    see all
  • 功能Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).
  • 组织特异性Widely expressed. Highly expressed in kidney, salivary gland and liver. Detected in trachea, stomach, brain, lung, prostate, placenta, mammary gland, small intestine and lung.
  • 序列相似性Belongs to the aldo/keto reductase family.
  • Information by UniProt

Human AKR1A1 peptide (ab23210)参考文献

ab23210 has not yet been referenced specifically in any publications.

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