概述

描述

  • 性质Synthetic
  • 氨基酸序列 1
    • 种属Human
    • 序列C-ATEGQVRVNSIYQDKVSL
    • 氨基酸89 to 106
    氨基酸序列 2
    • 种属Human
    • 序列C-ATEGQVRVNSIYQDKVSL
    • 氨基酸89 to 106

技术指标

Our Abpromise guarantee covers the use of ab39785 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

    Neutralising

  • 纯度> 90 % SDS-PAGE.
    This peptide is greater than 70% pure.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

常规信息

  • 别名
    • ACAN
    • AGC 1
    • AGC1
    • AGCAN
    • Aggrecan 1
    • Aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122)
    • Aggrecan core protein
    • Aggrecan proteoglycan
    • Aggrecan structural proteoglycan of cartilage
    • Aggrecan1
    • ATEGQV
    • Cartilage specific proteoglycan core protein
    • Chondroitin sulfate proteoglycan 1
    • Chondroitin sulfate proteoglycan 1 large aggregating proteoglycan antigen identified by monoclonal antibody A0122
    • Chondroitin sulfate proteoglycan core protein 1
    • CSPG 1
    • CSPG1
    • CSPGCP
    • JSCATE
    • Large aggregating proteoglycan
    • mcspg
    • mgsk16
    • MSK 16
    • MSK16
    • SEDK
    see all
  • 相关性Aggrecan is a member of a family of large, aggregating proteoglycans (also including versican, brevican and neurocan) which is found in articular cartilage. Aggrecan is composed of three major domains: G1, G2, and G3. Between the G1 and G2 domains there is an interglobulin region (IGD). The IGD region is the major site of cleavage by specific proteases like metalloproteinases (MMPs) and aggrecanase. Aggrecan cleavage has been associated with a number of degenerative diseases including rheumatoid arthritis and osteoarthritis. There is evidence that this family of proteoglycans modulates cell adhesion, migration, and axonal outgrowth in the CNS.
  • 细胞定位Secreted; extracellular matrix.

Human Aggrecan peptide (ab39785)参考文献

ab39785 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"