概述

  • 产品名称Anti-HUCE1抗体
    参阅全部 HUCE1 一抗
  • 描述
    小鼠多克隆抗体to HUCE1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length Human HUCE1 (NP_056139.1)

  • 阳性对照
    • HeLa cell lysate, HUCE1 transfected 293T cell lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab89478 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 51 kDa.

靶标

  • 功能Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.
  • 序列相似性Belongs to the methyltransferase superfamily. RRP8 family.
  • 细胞定位Nucleus > nucleolus. Localizes at rDNA locus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Cerebral protein 1 antibody
    • hypothetical protein LOC23378 antibody
    • KIAA0409 antibody
    • Nucleomethylin antibody
    • Ribosomal RNA processing 8 methyltransferase homolog antibody
    • Ribosomal RNA processing 8, methyltransferase, homolog (yeast) antibody
    • Ribosomal RNA processing protein 8 antibody
    • Ribosomal RNA-processing protein 8 antibody
    • RRP 8 antibody
    • RRP8 antibody
    • RRP8 methyltransferase homolog antibody
    • RRP8_HUMAN antibody
    see all

Anti-HUCE1 antibody 图像

Anti-HUCE1 antibody (ab89478)参考文献

ab89478 has not yet been referenced specifically in any publications.

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