Anti-HtrA3抗体- Catalytic domain (ab65911)
Key features and details
- Rabbit polyclonal to HtrA3 - Catalytic domain
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-HtrA3抗体- Catalytic domain
参阅全部 HtrA3 一抗 -
描述
兔多克隆抗体to HtrA3 - Catalytic domain -
宿主
Rabbit -
特异性
ab65911 recognizes both of the isoforms of HtrA3. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide based on the catalytic domain of human HtrA3.
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阳性对照
- Extracts of SW 620 in Serum Free, or treated with TPA, IL 1-Alpha, or IL 1-Beta.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: PBS, 50% Glycerol, 2.9% Sodium chloride -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab65911于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
说明 |
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Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
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功能
Probable serine protease. -
组织特异性
Widely expressed, with highest levels in both adult and fetal heart, ovary, uterus placenta, and bladder. Isoform 1 is predominant in heart and skeletal muscle, whereas isoform 2 is predominant in placenta and kidney. -
序列相似性
Belongs to the peptidase S1B family.
Contains 1 IGFBP N-terminal domain.
Contains 1 Kazal-like domain.
Contains 1 PDZ (DHR) domain. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 94031 Human
- Omim: 608785 Human
- SwissProt: P83110 Human
- Unigene: 479119 Human
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别名
- High temperature requirement factor A3 antibody
- High-temperature requirement factor A3 antibody
- HtrA serine peptidase 3 antibody
see all
图片
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All lanes : Anti-HtrA3 antibody - Catalytic domain (ab65911) at 1/1000 dilution
Lane 1 : SW 620 with SF
Lane 2 : SW 620 with TPA
Lane 3 : SW 620 with IL 1-Alpha
Lane 4 : SW 620 with IL 1-Beta
Lane 5 : Molecular weight markers
Predicted band size: 50 , 38 kDa
Observed band size: 40,48 kDa why is the actual band size different from the predicted?
Multiple additonal bands are observed. We are unsure as to the identity of these extra bands.
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab65911 被引用在 1 文献中.
- Russell TM & Johnson BJ Lyme disease spirochaetes possess an aggrecan-binding protease with aggrecanase activity. Mol Microbiol 90:228-40 (2013). PubMed: 23710801