Anti-HTLV I gp46抗体[68/4.11.21] (ab9083)

概述

  • 产品名称Anti-HTLV I gp46抗体[68/4.11.21]
    参阅全部 HTLV I gp46 一抗
  • 描述
    小鼠单克隆抗体[68/4.11.21] to HTLV I gp46
  • 特异性Reacts with Human T-Lymphotropic Virus Type I (HTLV I) surface protein, gp46. Reacts strongly with MTA-4 recombinant HTLV I env. No reactivity with the surface protein of HTLV II (MoT) has been observed.
  • 经测试应用适用于: Radioimmunoprecipitation, WB, ELISA, ICC/IFmore details
  • 表位The epitope is located between amino acids 190-209 of the viral env gene.
  • 常规说明


    The antibody is used to detect HTLV I surface protein and its precursor in lysates prepared from virons or infected cells. Using immunoblotting and/or radioimmunoprecipitation analysis, the biosynthesis and metabolism of viral surface protein may be studied.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • 纯度Ammonium Sulphate Precipitation
  • 纯化说明Purified from serum-free culture supernatant.
  • Primary antibody说明The antibody is used to detect HTLV I surface protein and its precursor in lysates prepared from virons or infected cells. Using immunoblotting and/or radioimmunoprecipitation analysis, the biosynthesis and metabolism of viral surface protein may be studied.
  • 克隆单克隆
  • 克隆编号68/4.11.21
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab9083 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Radioimmunoprecipitation Use at an assay dependent dilution.
WB Use a concentration of 1 - 10 µg/ml.
ELISA Use at an assay dependent dilution.
ICC/IF Use a concentration of 1 - 10 µg/ml.

靶标

  • 相关性HTLV I gp46 surface protein is processed from its precursor gp62. It attaches the virus to the host cell by binding to its receptor. This interaction triggers the refolding of the transmembrane protein (TM) and is thought to activate its fusogenic potential by unmasking its fusion peptide. Fusion occurs at the host cell plasma membrane.
  • 细胞定位Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein
  • 别名
    • Glycoprotein 46 antibody
    • SU antibody
    • Surface protein antibody

Anti-HTLV I gp46 antibody [68/4.11.21] (ab9083)参考文献

ab9083 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"