Anti-HTLV I gp46抗体[65/6C2.2.34] (ab9086)

概述

  • 产品名称
    Anti-HTLV I gp46抗体[65/6C2.2.34]
    参阅全部 HTLV I gp46 一抗
  • 描述
    小鼠单克隆抗体[65/6C2.2.34] to HTLV I gp46
  • 特异性
    Human T-Lymphotropic Virus Type I (HTLV I) surface protein, gp46 and with MTA-4 recombinant HTLV I env. Reacts with formalin fixed tissue. Cross-reactivity with the surface protein HTLV II (moT) has been observed.
  • 经测试应用
    适用于: WB, Radioimmunoprecipitation, ELISA, ICC/IFmore details
  • 免疫原

    Synthetic peptide corresponding to HTLV I gp46 aa 210-306.

  • 表位
    The epitope is located between amino acids 210-306 of the viral env gene.
  • 常规说明

    The antibody is used to detect HTLV I surface protein and its precursor in lysates prepared from virons or infected cells. Using immunoblotting and/or radioimmunoprecipitation analysis, the biosynthesis and metabolism of viral surface protein may be studied.

    Antibody dilutions should be prepared using buffers containing suitable protein in order to stabilize antibody activity.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 纯度
    Ammonium Sulphate Precipitation
  • 纯化说明
    Purified from serum-free culture supernatant. The antibody is greater than 85% pure as determined using denaturing polyacrylamide gel electrophoresis.
  • Primary antibody说明
    The antibody is used to detect HTLV I surface protein and its precursor in lysates prepared from virons or infected cells. Using immunoblotting and/or radioimmunoprecipitation analysis, the biosynthesis and metabolism of viral surface protein may be studied.
  • 克隆
    单克隆
  • 克隆编号
    65/6C2.2.34
  • 同种型
    IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab9086 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 10 µg/ml.
Radioimmunoprecipitation Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.
ICC/IF Use a concentration of 1 - 10 µg/ml.

靶标

  • 相关性
    HTLV I gp46 surface protein is processed from its precursor gp62. It attaches the virus to the host cell by binding to its receptor. This interaction triggers the refolding of the transmembrane protein (TM) and is thought to activate its fusogenic potential by unmasking its fusion peptide. Fusion occurs at the host cell plasma membrane.
  • 细胞定位
    Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein
  • 别名
    • Glycoprotein 46 antibody
    • SU antibody
    • Surface protein antibody

文献

ab9086 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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