概述

  • 产品名称Anti-HSV2 ICP4抗体
    参阅全部 HSV2 ICP4 一抗
  • 描述
    兔多克隆抗体to HSV2 ICP4
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Other
  • 免疫原

    A synthetic peptide corresponding to C terminal residues of Human HSV2 ICP4

性能

应用

Our Abpromise guarantee covers the use of ab96432 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 135 kDa. for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA 1/2000 - 1/5000.

靶标

  • 相关性ICP4 (Trans-acting transcriptional protein ICP4) is a transcriptional transactivator that binds with high affinity to the sequence 5'-ATCGTC-3'. ICP4 may interact with and recruit specific components of the general transcription machinery to viral promoters and stabilize their formation for transcription initiation. ICP4 negatively regulates its own transcription. This immediate early (EI) protein may be necessary in virion for viral pathogenesis. ICP4 is a homodimer and interacts with transcriptional regulator ICP27; this interaction is required for proper incorporation of ICP4 into virions. The long stretch of Ser is a major site of phosphorylation. Only the phosphorylated forms are capable of interacting with beta or gamma genes. ICP4 belongs to the herpesviridae ICP4/IE140/IE180 family.
  • 别名
    • Alpha 4 protein antibody
    • Alpha4 protein antibody
    • ICP4 antibody
    • IE175 antibody
    • Infected cell protein 4 antibody
    • RS1 antibody
    • Trans acting transcriptional protein ICP4 antibody
    • Transcriptional activator IE175 antibody
    • Transcriptional regulator ICP4 antibody
    see all

Anti-HSV2 ICP4 antibody (ab96432)参考文献

ab96432 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab96432.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"