Anti-Hsp90 beta抗体, prediluted (ab54266)

概述

  • 产品名称Anti-Hsp90 beta抗体, prediluted
    参阅全部 Hsp90 beta 一抗
  • 描述
    兔多克隆抗体to Hsp90 beta, prediluted
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Cow, Cynomolgus Monkey, Asian Toad (Bufo)
  • 免疫原

    Synthetic peptide:

    PEEVHHGEEEVE

    , corresponding to N terminal amino acids 2-13 of Mouse Hsp90 beta

  • 阳性对照
    • MAD109 cells or breast carcinoma

性能

应用

Our Abpromise guarantee covers the use of ab54266 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: Use at an assay dependent dilution. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

    Working dilution: Ready-to-use for 30 min at RT
    Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
    The optimal dilution for a specific application should be determined by the investigator.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
    • 序列相似性Belongs to the heat shock protein 90 family.
    • 结构域The TPR repeat-binding motif mediates interaction with TPR repeat-containing proteins.
    • 翻译后修饰Ubiquitinated in the presence of STUB1-UBE2D1 complex (in vitro).
      ISGylated.
      S-nitrosylated; negatively regulates the ATPase activity.
    • 细胞定位Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 90 kda heat shock protein beta HSP90 beta antibody
      • D6S182 antibody
      • FLJ26984 antibody
      • Heat shock 84 kDa antibody
      • Heat shock 90kD protein 1, beta antibody
      • Heat shock 90kDa protein 1 beta antibody
      • Heat shock protein 90kDa alpha (cytosolic) class B member 1 antibody
      • Heat shock protein beta antibody
      • Heat shock protein HSP 90 beta antibody
      • Heat shock protein HSP 90-beta antibody
      • HS90B_HUMAN antibody
      • HSP 84 antibody
      • HSP 90 antibody
      • HSP 90 b antibody
      • HSP 90b antibody
      • HSP84 antibody
      • HSP90 BETA antibody
      • hsp90ab1 antibody
      • HSP90B antibody
      • HSPC2 antibody
      • HSPCB antibody
      see all

    Anti-Hsp90 beta antibody, prediluted 图像

    • Human breast carcinoma stained with anti-Hsp90 beta (ab54266)

    Anti-Hsp90 beta antibody, prediluted (ab54266)参考文献

    ab54266 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"