Anti-Hsp90抗体(Biotin) (ab79649)

概述

  • 产品名称Anti-Hsp90抗体(Biotin)
    参阅全部 Hsp90 一抗
  • 描述
    兔多克隆抗体to Hsp90 (Biotin)
  • 偶联物Biotin
  • 经测试应用适用于: WB, ELISA, RIAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length Hsp90 protein (Human) expressed in E. coli.

性能

应用

Our Abpromise guarantee covers the use of ab79649 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Predicted molecular weight: 83 kDa.
ELISA Use a concentration of 3 - 8 µg/ml.
RIA Use a concentration of 3 - 8 µg/ml.

靶标

  • 功能Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
  • 序列相似性Belongs to the heat shock protein 90 family.
  • 结构域The TPR repeat-binding motif mediates interaction with TPR repeat-containing proteins like the co-chaperone STUB1.
  • 翻译后修饰ISGylated.
    S-nitrosylated; negatively regulates the ATPase activity and the activation of eNOS by HSP90AA1.
  • 细胞定位Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Heat shock 86 kDa antibody
    • Heat shock protein 90kDa alpha cytosolic class A member 1 antibody
    • Heat shock protein 90kDa alpha cytosolic class B member 1 antibody
    • Heat shock protein HSP 90 alpha antibody
    • Heat shock protein HSP 90 beta antibody
    • Heat shock protein HSP 90-alpha antibody
    • HS90A_HUMAN antibody
    • HSP 84 antibody
    • HSP 86 antibody
    • Hsp 90 antibody
    • HSP86 antibody
    • HSP90A antibody
    • HSP90AA1 antibody
    • HSP90AB1 antibody
    • HSP90B antibody
    • HSPC1 antibody
    • HSPC2 antibody
    • HSPCAL1 antibody
    • HSPCAL4 antibody
    • Renal carcinoma antigen NY-REN-38 antibody
    see all

Anti-Hsp90 antibody (Biotin) 图像

  • ab79649 ELISA human Hsp90 antibody assay performance. Assay was performed using increasing concentrations of biotinylated recombinant human Hsp90 protein. The antibody sensitivity is at 2 ng/mL.

Anti-Hsp90 antibody (Biotin) (ab79649)参考文献

ab79649 has not yet been referenced specifically in any publications.

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