FITC荧光Anti-Hsp70抗体[C92F3A-5] (ab61907)
Key features and details
- FITC Mouse monoclonal [C92F3A-5] to Hsp70
- Suitable for: Flow Cyt, IHC-P
- Reacts with: Mouse, Human
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG
Related conjugates and formulations
概述
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产品名称
FITC荧光Anti-Hsp70抗体[C92F3A-5]
参阅全部 Hsp70 一抗 -
描述
FITC荧光小鼠单克隆抗体[C92F3A-5] to Hsp70 -
宿主
Mouse -
偶联物
FITC. Ex: 493nm, Em: 528nm -
特异性
ab61907 detects a 70kDa protein corresponding to the molecular mass of inducible hsp70 on SDS PAGE immunoblots. There is no cross-reactivity to hsc70 (hsp73). -
经测试应用
适用于: Flow Cyt, IHC-Pmore details -
种属反应性
与反应: Mouse, Human -
免疫原
Full length protein. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- IHC-P: Mouse colon cancer tissue; human colon cancer tissue. Flow cyt: Heat Shocked CD3+ CD8+ T cells
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
Constituents: PBS, 0.75% 2-Ethanolamin, 0.08% Sodium bicarbonate, 4.5% Dimethylsulfoxide -
Concentration information loading...
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纯度
Protein G purified -
克隆
单克隆 -
克隆编号
C92F3A-5 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab61907于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
Flow Cyt |
1/1000.
|
|
IHC-P |
1/10000.
|
说明 |
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Flow Cyt
1/1000. |
IHC-P
1/10000. |
靶标
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相关性
Function: In cooperation with other chaperones, the Hsp70 family stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell. Tissue specificity: HSPA1B is testis-specific. -
细胞定位
Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. -
数据库链接
- Entrez Gene: 15511 Human
- Entrez Gene: 3303 Human
- Entrez Gene: 193740 Mouse
- Entrez Gene: 3304 Mouse
- Omim: 140550 Human
- Omim: 603012 Human
- SwissProt: P0DMV8 Human
- SwissProt: P0DMV9 Human
see all -
别名
- DnaK type molecular chaperone HSP70 1 antibody
- Epididymis secretory protein Li 103 antibody
- FLJ54303 antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab61907 被引用在 4 文献中.
- Ibrahim AG et al. Engineered extracellular vesicles antagonize SARS-CoV-2 infection by inhibiting mTOR signaling. Biomater Biosyst 6:100042 (2022). PubMed: 35187508
- Zhou B et al. Assisting anti-PD-1 antibody treatment with a liposomal system capable of recruiting immune cells. Nanoscale 11:7996-8011 (2019). PubMed: 30969294
- Manukyan G et al. Accelerated apoptosis of neutrophils in familial mediterranean Fever. Front Immunol 6:239 (2015). PubMed: 26042122
- Weiss LM et al. Bradyzoite development in Toxoplasma gondii and the hsp70 stress response. Infect Immun 66:3295-302 (1998). PubMed: 9632598