概述

  • 产品名称Anti-Hsp70抗体
    参阅全部 Hsp70 一抗
  • 描述
    兔多克隆抗体to Hsp70
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Rat
    预测可用于: Mouse, Cow, Dog, Human, Drosophila melanogaster, Fish
  • 免疫原

    Synthetic peptide derived from the sequence of Rat Hsp70.

  • 阳性对照
    • Mouse 3T3 and heat shocked 3T3 cell lysates; Purified Hsp70 protein and purified Hsc70 protein; Human Spleen neutrophils

性能

应用

Our Abpromise guarantee covers the use of ab109689 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Predicted molecular weight: 70 kDa.
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
  • 组织特异性HSPA1B is testis-specific.
  • 序列相似性Belongs to the heat shock protein 70 family.
  • 细胞定位Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DnaK type molecular chaperone HSP70 1 antibody
    • Epididymis secretory protein Li 103 antibody
    • FLJ54303 antibody
    • FLJ54370 antibody
    • FLJ54392 antibody
    • FLJ54408 antibody
    • FLJ75127 antibody
    • Heat shock 70 kDa protein 1 antibody
    • Heat shock 70 kDa protein 1/2 antibody
    • Heat shock 70 kDa protein 1A/1B antibody
    • Heat shock 70kDa protein 1A antibody
    • Heat shock 70kDa protein 1B antibody
    • Heat shock induced protein antibody
    • HEL S 103 antibody
    • HSP70 1 antibody
    • HSP70 1B antibody
    • HSP70 2 antibody
    • HSP70-1/HSP70-2 antibody
    • HSP70-1A antibody
    • HSP70.1 antibody
    • HSP70.1/HSP70.2 antibody
    • HSP70I antibody
    • HSP71_HUMAN antibody
    • HSP72 antibody
    • HSPA1 antibody
    • HSPA1A antibody
    • HSPA1B antibody
    see all

Anti-Hsp70 antibody 图像

  • All lanes : Anti-Hsp70 antibody (ab109689) at 1/1000 dilution

    Lane 1 : 3T3 cell lysate
    Lane 2 : Heat shocked 3T3 cell lysate
    Lane 3 : Purified Hsp70 protein
    Lane 4 : Purified Hsc70 protein


    Predicted band size : 70 kDa
  • ab109689, at 10 µg/ml, staining Hsp70 + Hsc70 in formalin-fixed, paraffin-embedded Human Spleen neutrophils by Immunohistochemistry.

Anti-Hsp70 antibody (ab109689)参考文献

ab109689 has not yet been referenced specifically in any publications.

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