概述

  • 产品名称Anti-Hsp70抗体[3A3]
    参阅全部 Hsp70 一抗
  • 描述
    小鼠单克隆抗体[3A3] to Hsp70
  • 经测试应用适用于: ICC/IF, IHC-P, IHC-Fr, WB, IPmore details
  • 种属反应性
    与反应: Mouse, Rat, Chicken, Human, Saccharomyces cerevisiae, Drosophila melanogaster, Fish
    预测可用于: Amphibians
  • 免疫原

    Recombinant full length protein (Human) expressed in E.coli.

性能

应用

Our Abpromise guarantee covers the use of ab74084 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF 1/500.
IHC-P Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.
WB 1/5000. Detects a band of approximately 70 kDa (predicted molecular weight: 70 kDa).
IP Use at an assay dependent concentration.

靶标

  • 功能In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
  • 组织特异性HSPA1B is testis-specific.
  • 序列相似性Belongs to the heat shock protein 70 family.
  • 细胞定位Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DnaK type molecular chaperone HSP70 1 antibody
    • Epididymis secretory protein Li 103 antibody
    • FLJ54303 antibody
    • FLJ54370 antibody
    • FLJ54392 antibody
    • FLJ54408 antibody
    • FLJ75127 antibody
    • Heat shock 70 kDa protein 1 antibody
    • Heat shock 70 kDa protein 1/2 antibody
    • Heat shock 70 kDa protein 1A/1B antibody
    • Heat shock 70kDa protein 1A antibody
    • Heat shock 70kDa protein 1B antibody
    • Heat shock induced protein antibody
    • HEL S 103 antibody
    • HSP70 1 antibody
    • HSP70 1B antibody
    • HSP70 2 antibody
    • HSP70-1/HSP70-2 antibody
    • HSP70-1A antibody
    • HSP70.1 antibody
    • HSP70.1/HSP70.2 antibody
    • HSP70I antibody
    • HSP71_HUMAN antibody
    • HSP72 antibody
    • HSPA1 antibody
    • HSPA1A antibody
    • HSPA1B antibody
    see all

Anti-Hsp70 antibody [3A3] 图像

  • Anti-Hsp70 antibody [3A3] (ab74084) at 1/1000 dilution + rat tissue lysate

    Secondary
    HRP-conjugated goat anti mouse

    Predicted band size : 70 kDa
    Observed band size : 70 kDa
    Additional bands at : 75 kDa. We are unsure as to the identity of these extra bands.

Anti-Hsp70 antibody [3A3] (ab74084)参考文献

This product has been referenced in:
  • Pernet L  et al. HDAC6-ubiquitin interaction controls the duration of HSF1 activation after heat shock. Mol Biol Cell 25:4187-94 (2014). WB ; Mouse . Read more (PubMed: 25298398) »

See 1 Publication for this product

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I am now back in the office and have reviewed this case for you. Regrettably, we have no other Hsp70 antibodies that have been tested in Drosophila or that have specifically been tested andguaranteed not to reac...

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