Anti-Hsp105抗体[EPR4577] (ab108625)


  • 产品名称Anti-Hsp105抗体[EPR4577]
    参阅全部 Hsp105 一抗
  • 描述
    兔单克隆抗体[EPR4577] to Hsp105
  • 经测试应用适用于: WB, IP, IHC-P, ICC/IFmore details
    不适用于: Flow Cyt
  • 种属反应性
    与反应: Human
  • 免疫原

    A synthetic peptide corresponding to residues in Human Hsp105.

  • 阳性对照
    • HeLa and HepG2 cell lysates; Human testis tissue; HeLa cells.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    A trial size is available to purchase for this antibody.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Alternative versions available:

    Anti-Hsp105 antibody (HRP) [EPR4577] (ab201246)

    Anti-Hsp105 antibody (Alexa Fluor® 488) [EPR4577] (ab201245)



Our Abpromise guarantee covers the use of ab108625 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/10000 - 1/50000. Predicted molecular weight: 97 kDa.
IP 1/10 - 1/100.
IHC-P 1/100 - 1/250. Antigen retrieval is recommended.
ICC/IF 1/100 - 1/250.
  • 应用说明Is unsuitable for Flow Cyt.
  • 靶标

    • 功能Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities.
    • 组织特异性Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.
    • 序列相似性Belongs to the heat shock protein 70 family.
    • 翻译后修饰Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.
    • 细胞定位Cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Antigen NY CO 25 antibody
      • Antigen NY-CO-25 antibody
      • DKFZp686M05240 antibody
      • Heat shock 105kD alpha antibody
      • Heat shock 105kD antibody
      • Heat shock 105kD beta antibody
      • Heat shock 105kDa protein 1 antibody
      • Heat shock 105kDa protein antibody
      • Heat shock 105kDa/110kDa protein 1 antibody
      • Heat shock 110 kDa protein antibody
      • Heat shock 110kDa protein antibody
      • Heat shock protein 105 kDa antibody
      • HS105_HUMAN antibody
      • HSP105 antibody
      • HSP105A antibody
      • HSP105B antibody
      • HSP110 antibody
      • HSPH 1 antibody
      • Hsph1 antibody
      • KIAA0201 antibody
      • NY CO 25 antibody
      see all

    Anti-Hsp105 antibody [EPR4577] 图像

    • All lanes : Anti-Hsp105 antibody [EPR4577] (ab108625) at 1/10000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : HepG2 cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size : 97 kDa
    • ab108625 at 1/100 dilution staining Hsp105 in Human testis by Immunohistochemistry, Paraffin-embedded tissue.
    • ab108625 at 1/100 dilution staining Hsp105 in HeLa cells by Immunofluorescence.

    Anti-Hsp105 antibody [EPR4577] (ab108625)参考文献

    ab108625 has not yet been referenced specifically in any publications.

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