兔单克隆抗体[EPR4577] to Hsp105
Synthetic peptide within Human Hsp105 aa 800-900. The exact sequence is proprietary.
- HeLa and HepG2 cell lysates; Human testis tissue; HeLa cells.
A trial size is available to purchase for this antibody.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents
This product is a recombinant rabbit monoclonal antibody.
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Tissue culture supernatant
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||1/10000 - 1/50000. Predicted molecular weight: 97 kDa.
||1/10 - 1/100.
||1/100 - 1/250. Antigen retrieval is recommended.
||1/100 - 1/250.
Is unsuitable for Flow Cyt.
Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities.
Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.
Belongs to the heat shock protein 70 family.
Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.
Information by UniProt
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Western blot - Anti-Hsp105 antibody [EPR4577] (ab108625)
All lanes : Anti-Hsp105 antibody [EPR4577] (ab108625) at 1/10000 dilution
Lane 1 : HeLa cell lysate
Lane 2 : HepG2 cell lysate
Lysates/proteins at 10 µg per lane.
Predicted band size: 97 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Hsp105 antibody [EPR4577] (ab108625)
ab108625 at 1/100 dilution staining Hsp105 in Human testis by Immunohistochemistry, Paraffin-embedded tissue.
Immunocytochemistry/ Immunofluorescence - Anti-Hsp105 antibody [EPR4577] (ab108625)
ab108625 at 1/100 dilution staining Hsp105 in HeLa cells by Immunofluorescence.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"