HsGAD67 ChIP探针(ab83613)

概述

性能

  • 功能Catalyzes the production of GABA.
  • 组织特异性Isoform 3 is expressed in pancreatic islets, testis, adrenal cortex, and perhaps other endocrine tissues, but not in brain.
  • 疾病相关Defects in GAD1 are the cause of cerebral palsy spastic quadriplegic type 1 (CPSQ1) [MIM:603513]. A non-progressive disorder of movement and/or posture resulting from defects in the developing central nervous system. Affected individuals manifest symmetrical, non-progressive spasticity and no adverse perinatal history or obvious underlying alternative diagnosis. Developmental delay, mental retardation and sometimes epilepsy can be part of the clinical picture.
  • 序列相似性Belongs to the group II decarboxylase family.
  • Information by UniProt
  • 别名
    • 67 kDa glutamic acid decarboxylase
    • CPSQ1
    • DCE1
    • DCE1_HUMAN
    • EC 4.1.1.15
    • FLJ45882
    • GAD
    • GAD 67
    • GAD-67
    • GAD1
    • Glutamate decarboxylase 1
    • Glutamate decarboxylase 1 (brain, 67kDa)
    • Glutamate decarboxylase 1 brain 67kD
    • Glutamate decarboxylase 1 brain 67kDa
    • Glutamate decarboxylase 67 kDa isoform
    • Glutamate decarboxylase, brain, 67-KD
    • OTTHUMP00000041055
    • SCP
    see all

应用

Our Abpromise guarantee covers the use of ab83613 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Real Time PCR Use at an assay dependent dilution. Suitable for the analysis of chromatin immunoprecipitated DNA using Taqman® real time PCR. The probe is labelled with FAM/TAMRA. Quantity provided for 200 reactions. Please see the protocol page for the instructions for this product.

HsGAD67 ChIP probe (ab83613)参考文献

ab83613 has not yet been referenced specifically in any publications.

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