概述

  • 产品名称Anti-HSD3B1抗体
    参阅全部 HSD3B1 一抗
  • 描述
    山羊多克隆抗体to HSD3B1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Cynomolgus Monkey, Rhesus monkey
  • 免疫原

    Synthetic peptide:

    C-DRHKETLKSKTQ

    , corresponding to C terminal amino acids 364-375 of Human HSD3B1

  • 阳性对照
    • Human Placenta lysate

性能

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应用

Our Abpromise guarantee covers the use of ab48018 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.01 - 0.1 µg/ml. Detects a band of approximately 42 kDa (predicted molecular weight: 42 kDa).

靶标

  • 功能3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. Efficiently catalyzes the transformation of pregnenolone to progesterone, 17-alpha-hydroxypregnenolone to 17-alpha-hydroxyprogesterone, DHEA to 4-androstenedione, dihydrotestosterone to 5-alpha-androstane-3 beta,17 beta-diol, dehydroepiandrosterone to androstenedione and 5-alpha-androstan-3 beta,17 beta-diol to 5-alpha-dihydrotestosterone.
  • 组织特异性Placenta and skin. Predominantly expressed in mammary gland tissue.
  • 通路Lipid metabolism; steroid biosynthesis.
  • 序列相似性Belongs to the 3-beta-HSD family.
  • 细胞定位Endoplasmic reticulum membrane. Mitochondrion membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 3 beta and steroid delta isomerase 1 antibody
    • 3 beta and steroid hydroxy delta 5 steroid dehydrogenase antibody
    • 3 beta HSD I antibody
    • 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I antibody
    • 3-beta-HSD I antibody
    • 3-beta-hydroxy-5-ene steroid dehydrogenase antibody
    • 3BETAHSD antibody
    • 3BH antibody
    • 3BHS1_HUMAN antibody
    • 3BHSD antibody
    • Delta-5-3-ketosteroid isomerase antibody
    • HGNC:5217 antibody
    • HSD3B antibody
    • HSD3B1 antibody
    • HSDB3 antibody
    • HSDB3A antibody
    • Hydroxy delta 5 steroid dehydrogenase 3 beta and steroid delta isomerase 1 antibody
    • Hydroxy delta 5 steroid dehydrogenase antibody
    • Progesterone reductase antibody
    • SDR11E1 antibody
    • Steroid Delta-isomerase antibody
    • trophoblast antigen antibody
    • Trophoblast antigen FDO161G antibody
    see all

Anti-HSD3B1 antibody 图像

  • Anti-HSD3B1 antibody (ab48018) at 0.01 µg/ml + Human Placenta lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 42 kDa
    Observed band size : 42 kDa

Anti-HSD3B1 antibody (ab48018)参考文献

ab48018 has not yet been referenced specifically in any publications.

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