概述

  • 产品名称Anti-HSD3a抗体
    参阅全部 HSD3a 一抗
  • 描述
    小鼠单克隆抗体to HSD3a
  • 经测试应用适用于: WB, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-324 of Human HSD3a

性能

应用

Our Abpromise guarantee covers the use of ab54606 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 37 kDa.
IHC-P Use a concentration of 3 µg/ml.
ICC/IF Use a concentration of 15 µg/ml.

靶标

  • 功能Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.
  • 组织特异性Liver specific.
  • 序列相似性Belongs to the aldo/keto reductase family.
  • 翻译后修饰The N-terminus is blocked.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 3 alpha HSD1 antibody
    • 3-alpha-HSD1 antibody
    • 3-alpha-hydroxysteroid dehydrogenase type I antibody
    • AK1C4_HUMAN antibody
    • AKR1C4 antibody
    • Aldo keto reductase family 1 member C4 antibody
    • Aldo-keto reductase family 1 member C4 antibody
    • CDR antibody
    • Chlordecone reductase antibody
    • DD-4 antibody
    • DD4 antibody
    • Dihydrodiol dehydrogenase 4 antibody
    • HAKRA antibody
    see all

Anti-HSD3a antibody 图像

  • HSD3a antibody (ab54606) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human liver tissue.


  • Predicted band size : 37 kDa
    HSD3a antibody (ab54606) at 1ug/lane + MCF-7 cell lysate at 25ug/lane.
  • ab54606 at 15 µg/ml staining HSD3a in human HepG2 cells by Immunocytochemistry / Immunofluorescence.

Anti-HSD3a antibody (ab54606)参考文献

ab54606 has not yet been referenced specifically in any publications.

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