概述

  • 产品名称Anti-HSD17B3抗体
    参阅全部 HSD17B3 一抗
  • 描述
    小鼠多克隆抗体to HSD17B3
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length human HSD17B3 protein (NP_000188.1)

  • 阳性对照
    • HSD17B3 transfected 293T cell lysate.

应用

Our Abpromise guarantee covers the use of ab70089 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 30 kDa (predicted molecular weight: 35 kDa).

靶标

  • 功能Favors the reduction of androstenedione to testosterone. Uses NADPH while the two other EDH17B enzymes use NADH.
  • 组织特异性Testis.
  • 通路Hormone biosynthesis; testosterone biosynthesis.
  • 疾病相关Defects in HSD17B3 are the cause of male pseudohermaphrodism with gynecomastia (MPH) [MIM:264300]. These individuals have unambiguous female external genitalia at birth, but fail to menstruate at the time of expected puberty and instead virilize as evidenced by growth of the phallus. Breast development may or may not take place.
  • 序列相似性Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 17 @beta HSD III antibody
    • 17 beta HSD 3 antibody
    • 17-@beta hydroxysteroid dehydrogenase III antibody
    • 17-beta-HSD 3 antibody
    • 17-beta-hydroxysteroid dehydrogenase type 3 antibody
    • DHB3_HUMAN antibody
    • EC 1.1.1.64 antibody
    • EDH17B3 antibody
    • Estradiol 17 beta dehydrogenase antibody
    • Estradiol 17 beta dehydrogenase 3 antibody
    • HSD17B3 antibody
    • Hydroxysteroid (17 beta) dehydrogenase 3 antibody
    • OTTHUMP00000021718 antibody
    • SDR12C2 antibody
    • Short chain dehydrogenase/reductase family 12C member 2 antibody
    • Testicular 17 @beta hydroxysteroid dehydrogenase III antibody
    • Testicular 17 beta hydroxysteroid dehydrogenase antibody
    • Testicular 17-beta-hydroxysteroid dehydrogenase antibody
    • Testosterone 17 beta dehydrogenase 3 antibody
    • Testosterone 17-beta-dehydrogenase 3 antibody
    see all

Anti-HSD17B3 antibody 图像

  • All lanes : Anti-HSD17B3 antibody (ab70089) at 1/500 dilution

    Lane 1 : HSD17B3 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 35 kDa
    Observed band size : 30 kDa (why is the actual band size different from the predicted?)

Anti-HSD17B3 antibody (ab70089)参考文献

ab70089 has not yet been referenced specifically in any publications.

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