Anti-HSC70 Interacting Protein HIP抗体[2G6] (ab2813)

概述

  • 产品名称Anti-HSC70 Interacting Protein HIP抗体[2G6]
    参阅全部 HSC70 Interacting Protein HIP 一抗
  • 描述
    小鼠单克隆抗体[2G6] to HSC70 Interacting Protein HIP
  • 经测试应用适用于: ICC/IF, IP, WBmore details
  • 种属反应性
    与反应: Mouse, Rabbit, Chicken, Human
  • 免疫原

    Other Immunogen Type corresponding to Human HSC70 Interacting Protein HIP. Recombinant human Hip protein.

  • 阳性对照
    • Rabbit reticulocyte lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.05% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • 纯度IgG fraction
  • 克隆单克隆
  • 克隆编号2G6
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab2813 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF 1/100 - 1/200.
IP Use at an assay dependent concentration.
WB Use a concentration of 1 µg/ml.

By Western blot, this antibody detects a 48 kDa protein representing Hip from rabbit reticulocyte lysate.

靶标

  • 功能One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins.
  • 序列相似性Belongs to the FAM10 family.
    Contains 1 STI1 domain.
    Contains 3 TPR repeats.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AAG 2 antibody
    • AAG2 antibody
    • Aging associated protein 2 antibody
    • F10A1_HUMAN antibody
    • FAM10A1 antibody
    • FAM10A4 antibody
    • FLJ27260 antibody
    • Heat shock 70kD protein binding protein antibody
    • Hip antibody
    • HOP antibody
    • Hsc70 interacting protein antibody
    • Hsc70-interacting protein antibody
    • Hsp70 interacting protein antibody
    • HSPABP 1 antibody
    • HSPABP antibody
    • HSPABP1 antibody
    • MGC129952 antibody
    • OTTHUMP00000028873 antibody
    • P48 antibody
    • PRO0786 antibody
    • Progesterone receptor associated p48 protein antibody
    • Progesterone receptor-associated p48 protein antibody
    • Protein FAM10A1 antibody
    • Putative tumor suppressor ST13 antibody
    • Renal carcinoma antigen NY REN 33 antibody
    • Renal carcinoma antigen NY-REN-33 antibody
    • SNC 6 antibody
    • SNC6 antibody
    • ST 13 antibody
    • St13 antibody
    • Suppression of tumorigenicity 13 antibody
    • Suppression of tumorigenicity 13 (colon carcinoma) antibody
    • Suppression of tumorigenicity 13 protein antibody
    • Suppression of tumorigenicity protein 13 antibody
    see all

Anti-HSC70 Interacting Protein HIP antibody [2G6] 图像

  • Immunocytochemistry/Immunofluorescence analysis of HSC70 Interacting Protein HIP in A431 cells. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with ab2813 (1:100) overnight at 4°C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody. HSC70 Interacting Protein HIP staining (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Images were taken at 60X magnification.

  • Immunocytochemistry/Immunofluorescence analysis of HSC70 Interacting Protein HIP in HeLa cells. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with ab2813 (1:20) overnight at 4°C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody. HSC70 Interacting Protein HIP staining (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Images were taken at 60X magnification.

  • Immunocytochemistry/Immunofluorescence analysis of HSC70 Interacting Protein HIP in NIH-3T3 cells. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with ab2813 (1:200) overnight at 4°C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody. HSC70 Interacting Protein HIP staining (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Images were taken at 60X magnification.

Anti-HSC70 Interacting Protein HIP antibody [2G6] (ab2813)参考文献

This product has been referenced in:
  • Prapapanich V  et al. Mutation of Hip's carboxy-terminal region inhibits a transitional stage of progesterone receptor assembly. Mol Cell Biol 18:944-52 (1998). Read more (PubMed: 9447991) »

See 1 Publication for this product

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