概述

  • 产品名称Anti-HRH3抗体
    参阅全部 HRH3 一抗
  • 描述
    兔多克隆抗体to HRH3
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Monkey
  • 免疫原

    Synthetic peptide, corresponding to a region within amino acids 293-357 of Human HRH3 (NP_009163).

  • 阳性对照
    • A431, H1299, HeLa and HepG2 cell lysates

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 20% Glycerol, 1% BSA, 1X PBS, pH 7.0
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab96787 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 48 kDa.

靶标

  • 功能The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 niether modified adenylate cyclase activity nor induced intracellular calcium mobilization.
  • 组织特异性Expressed predominantly in the CNS, with the greatest expression in the thalamus and caudate nucleus. The various isoforms are mainly coexpressed in brain, but their relative expression level varies in a region-specific manner. Isoform 3 and isoform 7 are highly expressed in the thalamus, caudate nucleus and cerebellum while isoform 5 and isoform 6 show a poor expression. Isoform 5 and isoform 6 show a high expression in the amygdala, substantia nigra, cerebral cortex and hypothalamus. Isoform 7 is not found in hypothalamus or substantia nigra.
  • 序列相似性Belongs to the G-protein coupled receptor 1 family.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • G protein coupled receptor 97 antibody
    • G-protein coupled receptor 97 antibody
    • GPCR 97 antibody
    • GPCR97 antibody
    • H3R antibody
    • HH 3R antibody
    • HH3 R antibody
    • HH3R antibody
    • Histamine H3 receptor antibody
    • Histamine receptor H3 antibody
    • HRH 3 antibody
    • HRH3 antibody
    • HRH3_HUMAN antibody
    • OTTHUMP00000031459 antibody
    see all

Anti-HRH3 antibody 图像

  • All lanes : Anti-HRH3 antibody (ab96787) at 1/1000 dilution

    Lane 1 : A431 whole cell lysate
    Lane 2 : H1299 whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 48 kDa

Anti-HRH3 antibody (ab96787)参考文献

ab96787 has not yet been referenced specifically in any publications.

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