概述

  • 产品名称Anti-HRH2抗体
    参阅全部 HRH2 一抗
  • 描述
    山羊多克隆抗体to HRH2
  • 特异性ab118279 is expected to recognize both reported isoforms (NP_001124527.1; NP_071640.1).
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide:

    SHNSHKTSLRLNNS

    with a Cysteine residue linker, corresponding to internal sequence amino acids 309-322 of Human HRH2 (NP_001124527.1; NP_071640.1).

  • 阳性对照
    • Human Duodenum and Ileum lysates.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 99% Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab118279 is purified from Goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab118279 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa).

靶标

  • 功能The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway.
  • 序列相似性Belongs to the G-protein coupled receptor 1 family.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Gastric receptor 1 antibody
    • Gastric receptor I antibody
    • H2R antibody
    • HGNC:5183 antibody
    • HH2R antibody
    • Histamine H2 receptor antibody
    • Histamine receptor H2 antibody
    • HRH2 antibody
    • HRH2_HUMAN antibody
    • OTTHUMP00000161242 antibody
    • OTTHUMP00000161243 antibody
    see all

Anti-HRH2 antibody 图像

  • Anti-HRH2 antibody (ab118279) at 0.1 µg/ml + Human Duodenum lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 45 kDa
    Observed band size : 45 kDa


    Exposure time : 1 hour

Anti-HRH2 antibody (ab118279)参考文献

ab118279 has not yet been referenced specifically in any publications.

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