Anti-HPV16 E6 + HPV18 E6抗体[C1P5], prediluted (ab51931)

概述

  • 产品名称Anti-HPV16 E6 + HPV18 E6抗体[C1P5], prediluted
    参阅全部 HPV16 E6 + HPV18 E6 一抗
  • 描述
    小鼠单克隆抗体[C1P5] to HPV16 E6 + HPV18 E6, prediluted
  • 特异性This antibody is specific for Human Papilloma virus Early Antigen E6, HPV 16 and 18
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human Papillomavirus (HPV)
  • 免疫原

    Human Papilloma virus Early Antigen E6, HPV types 16 und 18, b-galactosidase fusion protein.

  • 阳性对照
    • HPV-positive vulva carcinoma

性能

应用

Our Abpromise guarantee covers the use of ab51931 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration.

靶标

  • 相关性Human Papilloma virus (HPV) is responsible for the development of type and tissue specific papilloma in the oral cavity and in the larynx. In the skin papilloma virus can cause different types of warts and in the ano-genital region it is associated with condyloma or carcinoma. HPV types 1,6 and 11 usually are associated with benign transformations of the tissues, while e.g. HPV types 16, 18 and 31 seem to be responsible for the development of some carcinoma like cervical carcinoma. The role of HPV in non-melanoic tumours of the skin is under discussion. Protein E6 is a Transcriptional transactivator, binding double stranded DNA. It has transforming activity inactivating, with E6-AP ubiquitin-protein ligase, the human TP53/p53 tumor suppressor protein by targeting it for degradation.
  • 数据库链接
    • 别名
      • E6 antibody
      • Human Papilloma Virus antibody
      • Human papillomavirus type 16 E6 antibody
      • Human papillomavirus type 18 E6 antibody
      • Protein E6 antibody
      see all

    Anti-HPV16 E6 + HPV18 E6 antibody [C1P5], prediluted 图像

    • ab51931 staining HPV 16/18 in combinnation with biotinylated anti-mouse IgG, Streptavidin-AP and Fast Red staining. Retrieval method was antigen unmasking with citrate buffer pH 6 (2 x 5 min microwave oven 600 Watt). ab51931 was used undiluted, secondary AB 1:200, Streptavidin:AP 1:100.

    Anti-HPV16 E6 + HPV18 E6 antibody [C1P5], prediluted (ab51931)参考文献

    ab51931 has not yet been referenced specifically in any publications.

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    Both current lotswere identical in preparation and the final IgG concentration isapprox. 4.5 µg/ml.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"