Anti-HPSE2抗体(ab97807)

概述

  • 产品名称Anti-HPSE2抗体
    参阅全部 HPSE2 一抗
  • 描述
    兔多克隆抗体to HPSE2
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat
  • 免疫原

    Recombinant protein fragment with a sequence corresponding to a region within amino acids 260 and 552 of Human HPSE2 (NP_068600).

  • 阳性对照
    • 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji and NIH-3T3 cell lines. Paraffin-embedded lung AdCA.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab97807 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 67 kDa.
IHC-P Use at an assay dependent concentration.

靶标

  • 功能Binds heparin and heparan sulfate with high affinity, but lacks heparanase activity. Inhibits HPSE, possibly by competing for its substrates (in vitro).
  • 组织特异性Widely expressed, with the highest expression in brain, mammary gland, prostate, small intestine, testis and uterus. In the central nervous system, expressed in the spinal chord, caudate nucleus, thalamus, substantia nigra, medulla oblongata, putamen and pons. In the urinary bladder, expressed in longitudinal and circular layers of detrusor muscle. Found both in normal and cancer tissues.
  • 疾病相关Urofacial syndrome 1
  • 序列相似性Belongs to the glycosyl hydrolase 79 family.
  • 发展阶段Expressed in the developing forebrain, diencephalon, midbrain, hind brain and spinal cord at Carnagie stage 16 (CS16, 6 weeks of gestation) and CS21 (8 weeks).
  • 细胞定位Secreted, extracellular space, extracellular matrix.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FLJ11684 antibody
    • FLJ44022 antibody
    • heparanase 2 antibody
    • heparanase 3 antibody
    • heparanase-like protein antibody
    • Hpa2 antibody
    • HPR2 antibody
    • HPSE2 antibody
    • HPSE2_HUMAN antibody
    • Inactive heparanase-2 antibody
    • MGC133234 antibody
    • UFS antibody
    see all

Anti-HPSE2 antibody 图像

  • All lanes : Anti-HPSE2 antibody (ab97807) at 1/1000 dilution

    Lane 1 : 293T whole cell lysate
    Lane 2 : H1299 whole cell lysate
    Lane 3 : HeLa S3 whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 67 kDa
  • Anti-HPSE2 antibody (ab97807) at 1/1000 dilution + NIH-3T3 whole cell lysate at 30 µg

    Predicted band size : 67 kDa
  • ab97807, at 1/100, staining paraffin-embedded lung AdCA by Immunohistochemistry.

Anti-HPSE2 antibody (ab97807)参考文献

ab97807 has not yet been referenced specifically in any publications.

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Thank you once again for taking the time to complete our questionnaire and contact us. I am sorry to hear you have had difficulty obtaining satisfactory results from this antibody. The details you have kindly provided will enable us to investig...

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Thank you for contacting us. The immunogen that was used to produce ab97807 shows 100% identity with isoforms 1, 3 and 4 and 99% identity with isoform 2, so it likely recognizes all four isoforms. I hope this information is helpful to you. Plea...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"