概述

  • 产品名称
  • 描述
    兔多克隆抗体to HPS6
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Amino acids 405-466 of Human HPS6 (NP_079023)

    EEACGYYQRRSLRGAQLTPEELRHSSTFRAPQALASILQGHLPPSALLTM LRTELRDYRGLE

  • 阳性对照
    • H1299, HeLa and HepG2 cell lines. A431 whole cell lysate.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab96656 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Predicted molecular weight: 83 kDa.

靶标

  • 功能
    May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
  • 组织特异性
    Ubiquitous.
  • 疾病相关
    Defects in HPS6 are the cause of Hermansky-Pudlak syndrome type 6 (HPS6) [MIM:614075]. Hermansky-Pudlak syndrome (HPS) is a genetically heterogeneous, rare, autosomal recessive disorder characterized by oculocutaneous albinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects. This syndrome results from defects of diverse cytoplasmic organelles including melanosomes, platelet dense granules and lysosomes. Ceroid storage in the lungs is associated with pulmonary fibrosis, a common cause of premature death in individuals with HPS.
  • 细胞定位
    Microsome membrane. Cytoplasm > cytosol. Early endosome membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • BLOC2S3 antibody
    • FLJ22501 antibody
    • Hermansky Pudlak syndrome 6 protein antibody
    • Hermansky-Pudlak syndrome 6 protein antibody
    • HPS6 antibody
    • HPS6 biogenesis of lysosomal organelles complex 2 subunit 3 antibody
    • HPS6_HUMAN antibody
    • MGC20522 antibody
    • Ru antibody
    • Ruby eye protein homolog antibody
    • Ruby-eye protein homolog antibody
    see all

Anti-HPS6 antibody 图像

  • Anti-HPS6 antibody (ab96656) at 1/1000 dilution + A431 whole cell lysate at 30 µg

    Predicted band size : 83 kDa

实验方案

Anti-HPS6 antibody (ab96656)参考文献

ab96656 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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