概述

  • 产品名称Anti-HPS3抗体
    参阅全部 HPS3 一抗
  • 描述
    兔多克隆抗体to HPS3
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to a region within amino acids 992-1004 (

    PYLLYCSRKKPLT

    ) of Human HPS3 (NP_115759).

  • 阳性对照
    • 293T, A431, H1299, HeLa S3, HepG2, MOLT4 and Raji whole cell lysates; SW480 tissue

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab96343 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 114 kDa.
IHC-P 1/100 - 1/500.

靶标

  • 相关性HPS3 is involved in early stages of melanosome biogenesis and maturation. Defects in HPS3 are the cause of the cocoa (coa) mutant, and of Hermansky-Pudlak syndrome type 3 (HPS3). HPS3 is an autosomal recessive disorder, characterized by oculocutaneous albinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects. This syndrome results from defects of diverse cytoplasmic organelles including melanosomes, platelet dense granules and lysosomes. Ceroid storage in the lungs is associated with pulmonary fibrosis, a common cause of premature death in individuals with HPS.
  • 细胞定位Cytoplasmic
  • 数据库链接
  • 别名
    • Cocoa antibody
    • DKFZp686F0413 antibody
    • FLJ22704 antibody
    • Hermansky Pudlak syndrome 3 antibody
    • Hermansky Pudlak syndrome 3 protein antibody
    • SUTAL antibody
    see all

Anti-HPS3 antibody 图像

  • All lanes : Anti-HPS3 antibody (ab96343) at 1/1000 dilution

    Lane 1 : 293T whole cell lysate
    Lane 2 : A431 whole cell lysate
    Lane 3 : H1299 whole cell lysate
    Lane 4 : HeLa S3 whole cell lysate
    Lane 5 : HepG2 whole cell lysate
    Lane 6 : MOLT4 whole cell lysate
    Lane 7 : Raji whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 114 kDa
  • ab96343, at 1/500 dilution, staining HPS3 in paraffin-embedded SW480 by Immunohistochemistry.

Anti-HPS3 antibody (ab96343)参考文献

ab96343 has not yet been referenced specifically in any publications.

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