Anti-HP1BP3抗体(ab68719)
Key features and details
- Mouse polyclonal to HP1BP3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-HP1BP3抗体
参阅全部 HP1BP3 一抗 -
描述
小鼠多克隆抗体to HP1BP3 -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Recombinant full length protein within Human HP1BP3. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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阳性对照
- HP1BP3 transfected 293T lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
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纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab68719于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/1000. Detects a band of approximately 75 kDa (predicted molecular weight: 61 kDa).
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说明 |
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WB
1/500 - 1/1000. Detects a band of approximately 75 kDa (predicted molecular weight: 61 kDa). |
靶标
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功能
Component of heterochromatin that maintains heterochromatin integrity during G1/S progression and regulates the duration of G1 phase to critically influence cell proliferative capacity (PubMed:24830416). Mediates chromatin condensation during hypoxia, leading to increased tumor cell viability, radio-resistance, chemo-resistance and self-renewal(PubMed:25100860). -
序列相似性
Contains 3 H15 (linker histone H1/H5 globular) domains. -
结构域
A central region that included the first H15 (linker histone H1/H5 globular) domain binds at the entry/exit site of the nucleosomal DNA. -
细胞定位
Nucleus. Chromosome. localized in nuclei but not in nucleoli in interphase. Colocalized with chromosomes in mitosis, with a gradually increased during G1 progression and a maximum level during late G1 phase (G1/S). - Information by UniProt
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数据库链接
- Entrez Gene: 50809 Human
- SwissProt: Q5SSJ5 Human
- Unigene: 142442 Human
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别名
- Heterochromatin protein 1, binding protein 3 antibody
- Heterochromatin protein 1-binding protein 3 antibody
- HP1 BP74 antibody
see all
图片
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All lanes : Anti-HP1BP3 antibody (ab68719) at 1/500 dilution
Lane 1 : HP1BP3 transfected 293T lysate
Lane 2 : Non-transfected 293T lysate
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution
Predicted band size: 61 kDa
Observed band size: 75 kDa why is the actual band size different from the predicted?
数据表及文件
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Datasheet download
文献 (0)
ab68719 尚未被引用在任何文献中。