概述

  • 产品名称Anti-HP1 gamma抗体
    参阅全部 HP1 gamma 一抗
  • 描述
    兔多克隆抗体to HP1 gamma
  • 经测试应用适用于: IPmore details
    不适用于: WB
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Elephant
  • 免疫原

    Synthetic peptide corresponding to a region between residues 1 and 50 of human HP1 gamma (NP_009207.2).

  • 阳性对照
    • HeLa whole cell lysate.

性能

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应用

Our Abpromise guarantee covers the use of ab72041 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP
  • 应用说明IP: Use at 2-5µg/mg of lysate.

    Is unsuitable for WB.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
    • 序列相似性Contains 2 chromo domains.
    • 翻译后修饰Phosphorylated by PIM1. Phosphorylated during interphase and possibly hyper-phosphorylated during mitosis.
    • 细胞定位Nucleus. Associates with euchromatin and is largely excluded from constitutive heterochromatin. May be associated with microtubules and mitotic poles during mitosis.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CBX 3 antibody
      • CBX3 antibody
      • CBX3_HUMAN antibody
      • Chromobox homolog 3 (HP1 gamma homolog, Drosophila) antibody
      • Chromobox homolog 3 antibody
      • Chromobox protein homolog 3 antibody
      • GAMMA antibody
      • HECH antibody
      • Heterochromatin like protein 1 antibody
      • Heterochromatin protein 1 homolog gamma antibody
      • Heterochromatin protein HP1 gamma antibody
      • HP1 gamma antibody
      • HP1 gamma homolog antibody
      • HP1Hs gamma antibody
      • Modifier 2 protein antibody
      see all

    Anti-HP1 gamma antibody (ab72041)参考文献

    ab72041 has not yet been referenced specifically in any publications.

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