概述

  • 产品名称Anti-HOXA2抗体
    参阅全部 HOXA2 一抗
  • 描述
    兔多克隆抗体to HOXA2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within C terminal amino acids 220-269 (SEKVEEDEEE KTLFEQALSV SGALLEREGY TFQQNALSQQ QAPNGHNGDS) of Human HOXA2 (NP_006726).

  • 阳性对照
    • ACHN cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab119126 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 41 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
  • 疾病相关Defects in HOXA2 are a cause of microtia hearing impairment and cleft palate (MHICP) [MIM:612290]. Microtia is a congenital deformity of the outer ear and occurs in approximately one in 8'000-10'000 births. It is characterized by a small, abnormally shaped outer ear. It can be unilateral or bilateral. Syndromic forms of microtia occur in conjunction with other abnormalities. The most common associated malformations is the cleft palate, a congenital fissure of the soft and/or hard palate due to faulty fusion. Defects in HOXA2 are a cause of autosomal-recessive bilateral microtia, mixed symmetrical severe to profound hearing impairment and partial cleft palate.
  • 序列相似性Belongs to the Antp homeobox family. Proboscipedia subfamily.
    Contains 1 homeobox DNA-binding domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AI324701 antibody
    • homeo box A2 antibody
    • homeobox A2 antibody
    • Homeobox protein Hox-1K antibody
    • Homeobox protein Hox-A2 antibody
    • Hox-1.11 antibody
    • HOX1.11 antibody
    • HOX1K antibody
    • Hoxa-2 antibody
    • Hoxa11 antibody
    • HOXA2 antibody
    • HXA2_HUMAN antibody
    • MGC151482 antibody
    • MGC151484 antibody
    • RATHOX111A antibody
    see all

Anti-HOXA2 antibody 图像

  • Anti-HOXA2 antibody (ab119126) at 1 µg + ACHN cell lysate at 10 µg

    Predicted band size : 41 kDa

Anti-HOXA2 antibody (ab119126)参考文献

ab119126 has not yet been referenced specifically in any publications.

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