概述

  • 产品名称Anti-HOOK3抗体
    参阅全部 HOOK3 一抗
  • 描述
    小鼠单克隆抗体to HOOK3
  • 经测试应用适用于: WB, ELISA, IHC-P, Sandwich ELISAmore details
  • 种属反应性
    与反应: Human, Recombinant Fragment
  • 免疫原

    Recombinant fragment corresponding to amino acids 622-719 of Human HOOK3, NP_115786, with proprietary tag.

  • 阳性对照
    • Recombinant Protein, HOOK3 transfected lysate, Human placenta

性能

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应用

Our Abpromise guarantee covers the use of ab118091 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 83 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 3 µg/ml.
Sandwich ELISA Use a concentration of 10 µg/ml.

靶标

  • 功能Probably serves as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). May regulate clearance of endocytosed receptors such as MSR1. Participates in defining the architecture and localization of the Golgi complex.
  • 序列相似性Belongs to the hook family.
  • 细胞定位Cytoplasm > cytoskeleton. Golgi apparatus. Enriched at the cis-face of the Golgi complex (By similarity). Localizes to microtubule asters in prophase.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FLJ31058 antibody
    • h-hook3 antibody
    • hHK3 antibody
    • HK3 antibody
    • hook3 antibody
    • HOOK3_HUMAN antibody
    • OTTHUMP00000229200 antibody
    • Protein Hook homolog 3 antibody
    see all

Anti-HOOK3 antibody 图像

  • Anti-HOOK3 antibody (ab118091) at 1 µg/ml + Recombinant Protein at 0.1 µg
    Developed using the ECL technique

    Predicted band size : 83 kDa
  • All lanes : Anti-HOOK3 antibody (ab118091) at 1 µg/ml

    Lane 1 : HOOK3 transfected lysate
    Lane 2 : Non-transfected lysate

    Lysates/proteins at 25 µg per lane.

    Developed using the ECL technique

    Predicted band size : 83 kDa
  • Immunoperoxidase of ab118091 to HOOK3 on formalin-fixed paraffin-embedded Human placenta. [antibody concentration 3 µg/ml]
  • Detection limit for recombinant proprietary tagged HOOK3 is 1 ng/ml as a capture antibody. Antibody concentration : 10 µg/ml.

Anti-HOOK3 antibody (ab118091)参考文献

ab118091 has not yet been referenced specifically in any publications.

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