概述

  • 产品名称Anti-HOOK2抗体
    参阅全部 HOOK2 一抗
  • 描述
    兔多克隆抗体to HOOK2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 700 to the C-terminus of Mouse HOOK2.

    (Peptide available as ab101733.)

  • 阳性对照
    • This antibody gave a positive signal in human brain tissue lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab89696 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 83 kDa (predicted molecular weight: 83 kDa).

靶标

  • 相关性HOOK2 is a member of the Hook protein family. Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. HOOK2 localizes to the centrosome through all phases of the cell cycle. Interference with HOOK2 function results in the loss of the radial organization of microtubules suggesting that HOOK2 contributes to the establishment and maintenance of centrosomal structure and function. HOOK2 may contribute to the establishment and maintenance of the pericentrosomal localization of aggresomes by promoting the microtubule-based delivery of protein aggregates to pericentriolar aggresomes.
  • 细胞定位Cytoplasmic. Note=Associates with discrete punctate structure that correspond to neither early or late endosomes, lysosomes, multivesicular bodies (MVBs), Golgi complex, endoplasmic reticulum, nor mitochondria.
  • 数据库链接
  • 别名
    • A630054I03Rik antibody
    • FLJ26218 antibody
    • h hook2 antibody
    • hHK 2 antibody
    • hHK2 antibody
    • hhook 2 antibody
    • hhook2 antibody
    • HK 2 antibody
    • HK2 antibody
    • HOOK 2 antibody
    • hook homolog 2 (Drosophila) antibody
    • Hook homolog 2 antibody
    • MGC28586 antibody
    • MGC91008 antibody
    see all

Anti-HOOK2 antibody 图像

  • Anti-HOOK2 antibody (ab89696) at 1 µg/ml + Human brain tissue lysate - total protein (ab29466) at 10 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 83 kDa
    Observed band size : 83 kDa
    Additional bands at : 23 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 20 minutes

Anti-HOOK2 antibody (ab89696)参考文献

ab89696 has not yet been referenced specifically in any publications.

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